Paul Chaikin, professor at NYU, with the support of the Joliot Chair. Paul will give a seminar Thursday, June 11, in amphi Charpak at 3:00 p.m.
On Some small steps toward artificial Life.
Abstract: Self-replication and evolution under selective pressure are inherent phenomena in life, but few artificial systems exhibit these phenomena. We have designed a process and a system of DNA origami tiles that exponentially replicate a seed pattern, doubling (or more) the copies in each diurnal-like cycle of temperature and UV illumination, producing more than 6 million copies in 12 cycles with no enzymes or polymerases. We demonstrate environmental selection and competition. We also use DNA origami to self-assemble nano-micro machines that use oligonucleotides for fuel, and we make transcription modules for sensing and communication.
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